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Clinical Trial
. 1980;6(6):404-6.
doi: 10.1185/03007998009109459.

Single-dose cefuroxime in the prophylaxis of abdominal wound sepsis

Clinical Trial

Single-dose cefuroxime in the prophylaxis of abdominal wound sepsis

W G Lambert et al. Curr Med Res Opin. 1980.

Abstract

A double-blind study was carried out to investigate the prophylactic use of single-dose cefuroxime in elective abdominal surgery. Twenty-three patients received 1.5 g cefuroxime by intravenous injection immediately prior to induction of anaesthesia; 24 patients received no antibiotics. In the cefuroxime group, there were no cases of post-operative wound sepsis or septicaemia; in the control group, the incidence of these infections was 12.5% and 8.3% respectively.

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