Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 May;13(3):277-85.
doi: 10.1111/j.1365-2184.1980.tb00466.x.

Variability of short-term cultures of HeLa S-3 cells: changes in DNA distributions and rates of DNA synthesis

J M Collins, D E Berry, C B Bagwell

Variability of short-term cultures of HeLa S-3 cells: changes in DNA distributions and rates of DNA synthesis

J M Collins et al. Cell Tissue Kinet. 1980 May.

Abstract

DNA distributions of HeLa S-3 cells in spinner culture exhibit significant time-dependent changes. The major differences appear to occur in the S-phase region. Significant changes in the rates of DNA synthesis in several S-phase subcompartments correlated well with the changes in the DNA distributions. It is proposed that fluctuations in these rates of DNA synthesis are a reflection of the inherent instability of these abnormal, heteroploid cells.

PubMed Disclaimer

Publication types