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. 1980 Jan;156(4-5):477-82.
doi: 10.1016/S0171-2985(80)80081-7.

A long-lasting enhancing effect of anti-tuberculin antiserum on delayed-type hypersensitivity reaction in BCG-infected guinea pigs

H Mauch, H J Hammer, G Kümel

A long-lasting enhancing effect of anti-tuberculin antiserum on delayed-type hypersensitivity reaction in BCG-infected guinea pigs

H Mauch et al. Immunobiology. 1980 Jan.

Abstract

Anti-tuberculin serum and anti-BCG immunoglobulins from immunized guinea pigs were transferred into recipient guinea pigs which had been infected with BCG. An enhancement of tuberculin skin reactivity was observed 7 and 35 days after transfer of homologous antiserum in comparison to a control group. This indicates a modulating effect of humoral factors, presumably specific antibodies on the expression of delayed-type hypersensitivity reaction after immunostimulation with BCG.

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