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. 1980 Apr;77(4):1823-7.
doi: 10.1073/pnas.77.4.1823.

Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli

F E Nargang, C S Subrahmanyam, H E Umbarger

Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli

F E Nargang et al. Proc Natl Acad Sci U S A. 1980 Apr.

Abstract

The nucleotide sequence of the DNA thought to contain the control region for the ilvGEDA operon in Escherichia coli has been determined by the Maxam-Gilbert procedure. The sequence includes a region that, upon transcription, would yield a leader transcript specifying a peptide 32 residues long. This putative peptide would contain four leucine, five isoleucine, and six valine residues. A model is proposed that correlates the multivalent control of the ilvGEDA operon with the extent to which this leader transcript is translated. In vitro transcription experiments yielded a transcript of about 183 nucelotides, compatible with the predictions of the model.

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References

    1. Nature. 1969 Dec 6;224(5223):957-64 - PubMed
    1. Nat New Biol. 1972 Mar 22;236(64):71-5 - PubMed
    1. J Bacteriol. 1972 Oct;112(1):40-7 - PubMed
    1. Nat New Biol. 1973 Nov 14;246(150):40-1 - PubMed
    1. J Mol Biol. 1974 Jul 15;86(4):843-53 - PubMed

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