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. 1980 May 30;208(4447):1036-7.
doi: 10.1126/science.6990488.

Synthesis of human plasminogen by the liver

D Raum, D Marcus, C A Alper, R Levey, P D Taylor, T E Starzl

Synthesis of human plasminogen by the liver

D Raum et al. Science. .

Abstract

Genetic types of plasminogen were determined from a donor and a recipient before and after hepatic homotransplantation. Examination of the plasminogen types demonstrated that the liver is the principal site of synthesis of human plasminogen.

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Figures

Fig. 1
Fig. 1
(left). Plasminogen types in a donor (D) and recipient (R) before and after renal homotransplantation, demonstrated by caseinolytic overlay. From left to right: donor, recipient before transplantation, recipient 1 week after transplantation, and recipient 2 weeks after transplantation. Fig. 2 (right). Plasminogen types in a donor and recipient before and after liver homotransplantation, demonstrated by caseinolytic overlay. From left to right: donor, recipient before transplantation, recipient 1 month after transplantation, and recipient 6 months after transplantation. The specimen from the donor was obtained immediately prior to death, and it appeared to show reduced plasminogen activity at that time.
See this image and copyright information in PMC

References

    1. Starzl TE, Marchioro TL, Rowlands DT, Jr, Kirkpatrick CH, Wilson WEC, Rifkind D, Waddell WR. Ann Surg. 1964;160:411. - PMC - PubMed
    2. Kashiwagi N, Groth CG, Starzl TE. Proc Soc Exp Biol Med. 1968;128:247. - PMC - PubMed
    3. Alper CA, Johnson AM, Birtch AG, Moore FD. Science. 1969;163:286. - PubMed
    4. Hobart MJ, Lachmann PJ, Calne RY. J Exp Med. 1977;146:629. - PMC - PubMed
    5. Alper CA, Raum D, Awdeh ZL, Petersen BH, Taylor PD, Starzl TE. Clin Immunol Immunpathol. in press. - PubMed
    1. Barnhart MI, Riddle JM. Blood. 1963;21:306. - PubMed
    1. Mattii R, Ambrus JL, Sokal JE, Mink I. Proc Soc Exp Biol Med. 1964;116:69. - PubMed
    1. Prokopowicz J. Biochim Biophys Acta. 1968;154:91. - PubMed
    2. Prokopowicz J, Stormorken H. Scand J Haematol. 1968;5:129. - PubMed
    1. Sakuragawa N. Acta Haematol Jpn. 1966;29:910. - PubMed

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