Review
doi: 10.1086/409053.
The regulation of physiological changes during mammalian aging
- PMID: 6991
- DOI: 10.1086/409053
Item in Clipboard
Review
The regulation of physiological changes during mammalian aging
Q Rev Biol.
1976 Mar.
Abstract
Much evidence suggests that intrinsic molecular or cellular aging mechanisms need not be invoked to explain most age-related cellular changes and pathologcical conditions. Analysis of a widely scattered literature indicates that hormones and neural factors regulate a great number of cellular aging phenomena of mammals. It is proposed that age-related changes after maturation result from an extension of the neural and endocrine mechanisms that control earlier development and that produce a regulatory cascade of changing neural, endocrine, and target-tissue interactions.
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