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Comparative Study
. 1980 Mar;117(1):253-5.
doi: 10.1099/00221287-117-1-253.

Inhibition of sterol biosynthesis in Candida albicans by imidazole-containing antifungals

M S Marriott
Comparative Study

Inhibition of sterol biosynthesis in Candida albicans by imidazole-containing antifungals

M S Marriott. J Gen Microbiol. 1980 Mar.

Abstract

A simple procedure for studying sterol biosynthesis in cell-free homogenates of Candida albicans is described. The activities of some imidazole-containing antifungals (tioconazole, clotrimazole, econazole, ketoconazole and miconazole) as inhibitors of sterol C-14 demethylation have been determined using this technique.

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