Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1980;15(4):374-8.
doi: 10.1007/BF02774310.

Controlled trial of D-penicillamine with low dosis in the treatment of chronic liver diseases

H Nakano, S Ohnishi, T Sugiyama, M Miyamura, H Imura, Y Yamamoto, K Ito
Clinical Trial

Controlled trial of D-penicillamine with low dosis in the treatment of chronic liver diseases

H Nakano et al. Gastroenterol Jpn. 1980.

Abstract

Controlled trial of D-penicillamine was carried out with low dosis in 10 patients with chronic persistent hepatitis, 11 patients with chronic aggressive hepatitis and 7 patients with liver cirrhosis. After 6 weeks and 6 months treatment mean values of transaminases improved in patients with chronic persistent hepatitis. The mean serum transaminases levels of the patients with chronic aggressive hepatitis were statistically decreased after 6 weeks treatment but not significantly lower after 6 months treatment than on entry. D-penicillamine is not effective for the treatment of patients with liver cirrhosis. Eight of 36 patients treated were withdrawn from the trial because of adverse drug toxicity side effects.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. MMW Munch Med Wochenschr. 1974 Feb 1;116(5):217-20 - PubMed
    1. Lancet. 1973 Feb 10;1(7798):275-80 - PubMed
    1. Am J Med. 1956 Oct;21(4):487-95 - PubMed
    1. Med Klin. 1972 Oct 6;67(40):1277-82 - PubMed
    1. Verh Dtsch Ges Inn Med. 1974;80:1412-4 - PubMed

Publication types

LinkOut - more resources