Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Oct;144(1):274-8.
doi: 10.1128/jb.144.1.274-278.1980.

Substrate specificity and transport properties of the glycerol facilitator of Escherichia coli

K B Heller, E C Lin, T H Wilson

Substrate specificity and transport properties of the glycerol facilitator of Escherichia coli

K B Heller et al. J Bacteriol. 1980 Oct.

Abstract

The specificity of the glycerol facilitator (glpF) of Escherichia coli was studied with an osmotic method. This transport system allowed the entry of polyols (glycerol and erythritol), pentitols, and hexitols. The analogous sugars were not transported. However, urea, glycine, and DL-glyceraldehyde could use this pathway to enter the cell. The glpF protein allowed the rapid efflux of preequilibrated xylitol. Glycerol surprisingly did not inhibit the uptake of xylitol, and xylitol only slightly reduced the uptake of glycerol. The observation and the insensitivity of the xylitol transport to low temperature suggest that the facilitator behaves as a membrane channel.

PubMed Disclaimer

References

    1. Biochem Biophys Res Commun. 1968 Jul 26;32(2):344-9 - PubMed
    1. J Bacteriol. 1972 Nov;112(2):784-90 - PubMed
    1. J Gen Microbiol. 1974 May;82(1):125-42 - PubMed
    1. J Bacteriol. 1976 Oct;128(1):325-36 - PubMed
    1. Annu Rev Microbiol. 1976;30:535-78 - PubMed

Publication types

LinkOut - more resources