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. 1980 Jul;86(1):335-40.
doi: 10.1083/jcb.86.1.335.

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures

A Bretscher et al. J Cell Biol. 1980 Jul.

Abstract

A 68,000 mol wt polypeptide has been identified as one of the few major proteins in the microfilament bundles of the microvilli present on intestinal epithelial cells. Antibodies against the purified protein have been used in indirect immunofluorescence microscopy on several cultured cells. The protein have been used in indirect immunofluorescence microscopy on several cultured cells. The protein is found particularly prominent in membrane ruffles, microspikes, and microvilli.

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