[Pancreatic B cell peptides: kinetic behaviour and concentrations of proinsulin, insulin and C-peptide in plasma and urine, problems of assay methods, clinical significance and literature review (author's transl)]

Abstract

The kinetics and the concentrations of B-cell peptides in plasma and urine are reviewed. Methodical problems in the determination of proinsulin, free and antibody-bound insulin and C-peptide are discussed, together with the possible application of these methods in the control of insulin-dependent diabetics.