Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Sep;77(9):5064-8.
doi: 10.1073/pnas.77.9.5064.

Differential amplification of specific areas of phage T4 genome as revealed by hybridization to cloned genetic segments

A W Kozinski, S K Ling, N Hutchinson, M E Halpern, T Mattson

Differential amplification of specific areas of phage T4 genome as revealed by hybridization to cloned genetic segments

A W Kozinski et al. Proc Natl Acad Sci U S A. 1980 Sep.

Abstract

Under various conditions, specific genetic areas of the phage T4 DNA molecule are preferentially and repeatedly replicated, resulting in the amplification of these areas. These areas are found to lie in the vicinity of the known origins of DNA replication.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1965 Jul;54(1):273-8 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1968;33:375-91 - PubMed
    1. J Virol. 1967 Aug;1(4):758-70 - PubMed
    1. J Mol Biol. 1970 Nov 28;54(1):85-102 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Dec;68(12):3049-53 - PubMed

Publication types

LinkOut - more resources