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. 1980 Jun;61(2):87-9.
doi: 10.1016/0041-3879(80)90015-x.

Diagnostic potentialities of enzyme-linked immunosorbent assay in tuberculosis using purified tuberculin antigen

A Tandon, R P Saxena, K C Saxena, Z Jamil, A K Gupta

Diagnostic potentialities of enzyme-linked immunosorbent assay in tuberculosis using purified tuberculin antigen

A Tandon et al. Tubercle. 1980 Jun.

Abstract

Delayed hypersensitivity tests with tuberculin or purified tuberculin (PPD) have been used for detection of tuberculous infection. The present paper describes an enzyme-linked immunosorbent assay (ELISA) for detection of PPD-antibodies in tuberculosis patients. The ELISA test was positive in nearly 80% of cases having bacteriological evidence of tuberculosis. The test could also detect PPD-antibodies in 66% of the cases not showing bacteriological evidence of tuberculosis. The potentiality of the test in the immunodiagnosis of tuberculosis is discussed.

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