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Case Reports
. 1980 Nov 29;281(6253):1456-7.
doi: 10.1136/bmj.281.6253.1456.

Glial origin of rapidly adhering amniotic fluid cells

P Aula, H von Koskull, K Teramo, O Karjalainen, I Virtanen, V P Lehto, D Dahl
Case Reports

Glial origin of rapidly adhering amniotic fluid cells

P Aula et al. Br Med J. .

Abstract

Rapidly adhering cells (RA cells) from the amniotic fluid of a pregnancy with fetal anencephaly were investigated by immunofluorescence assay with an antiserum against glial cells. After 24 hours' cultivation a high proportion of the cells showed positive glial-specific fluorescence, whereas no staining was seen in cells from samples of normal amniotic fluid. At the 24th week the mother was delivered of a stillborn infant with anencephaly. Immunofluorescence staining of RA cells with glial-specific antiserum may be used for the differential diagnosis of fetal abnormalities associated with a high alpha-fetoprotein concentration in amniotic fluid.

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