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. 1980 Nov;30(2):321-4.
doi: 10.1128/iai.30.2.321-324.1980.

Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp

G Adamus, M Mulczyk, D Witkowska, E Romanowska

Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp

G Adamus et al. Infect Immun. 1980 Nov.

Abstract

Active immunization of guinea pigs and rabbits with outer membrane proteins (OMP) isolated from Shigella flexneri 3a and Shigella sonnei phase I protected the animals against keratoconjunctivitis shigellosa induced with the homologous or heterologous strain. Protection was also achieved in rabbits after passive immunization with anti-OMP immune serum. Active immunization with lipopolysaccharide of S. flexneri 3a did not protect rabbits against keratoconjunctivitis shigellosa.

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