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Clinical Trial
. 1980 Jul;56(657):488-90.
doi: 10.1136/pgmj.56.657.488.

Papaverine and hepatotoxicity

M S Pathy, A J Reynolds
Clinical Trial

Papaverine and hepatotoxicity

M S Pathy et al. Postgrad Med J. 1980 Jul.

Abstract

Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in clinical medicine for over 100 years.

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References

    1. N Engl J Med. 1969 Dec 11;281(24):1333-5 - PubMed
    1. N Engl J Med. 1969 Dec 11;281(24):1364-5 - PubMed
    1. J Am Geriatr Soc. 1970 Jun;18(6):507-12 - PubMed
    1. J Am Geriatr Soc. 1973 May;21(5):200-1 - PubMed
    1. J Am Geriatr Soc. 1973 May;21(5):202-5 - PubMed