Inhibition of Tritrichomonas foetus by vermiculine in vitro
- PMID: 700526
- DOI: 10.1007/BF02876441
Inhibition of Tritrichomonas foetus by vermiculine in vitro
Abstract
The macrolide aglycosidic antibiotic vermiculine, added to the cultivation medium to a concentration of 30 micogram/ml, has an in vitro inhibitory effect on Tritrichomonas foetus. The agent interacts rapidly with the cells, causing irreversible changes after several hours of action. The changes are not repaired on removing the agent; the cells suffer from a rapid inhibition of nucleic acid synthesis, the protein synthesis remaining intact.
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