Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1981 Jan;42(1):11-5.

Amoxapine and amitriptyline in the outpatient treatment of endogenous depression

P T Donlon, H Biertuemphel 3rd, M Willenbring
  • PMID: 7007357
Clinical Trial

Amoxapine and amitriptyline in the outpatient treatment of endogenous depression

P T Donlon et al. J Clin Psychiatry. 1981 Jan.

Abstract

This double-blind investigation compared onset of action, efficacy, and safety of amoxapine and amitriptyline in 46 endogenously depressed outpatients. Statistical analysis demonstrated relatively few significant differences in improvement between the two groups. Most of the differences favored amoxapine, however, and on all measures there were clear trends favoring amoxapine for more rapid onset of action or greater overall efficacy or both.

PubMed Disclaimer