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. 1981 Mar 19;290(5803):221-5.
doi: 10.1038/290221a0.

The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation

B Jaurin, T Grundström, T Edlund, S Normark

The E. coli beta-lactamase attenuator mediates growth rate-dependent regulation

B Jaurin et al. Nature. .

Abstract

We have identified a new control or attenuator region in the chromosomal beta-lactamase operon of Escherichia coli. A single base alteration within its attenuator led to a loss in the cell's ability to coordinate its content of beta-lactamase with growth rate. We suggest a mechanism through which this mode of regulation operates.

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