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Clinical Trial
. 1981 Feb;52(1):77-80.
doi: 10.3109/17453678108991763.

Low-dose heparin in proximal femoral fractures. Failure to prevent deep-vein thrombosis

Clinical Trial

Low-dose heparin in proximal femoral fractures. Failure to prevent deep-vein thrombosis

H Svend-Hansen et al. Acta Orthop Scand. 1981 Feb.

Abstract

The effect of heparin, 5000 units every 8 hours, on deep venous thrombosis in patients with proximal femoral fractures was investigated in a controlled, double blind, randomised study. Heparin or placebo was administered as soon as possible after the fracture, and before 6 hours had passed, and was continued for 14 days. The diagnosis of deep venous thrombosis was made using daily I125 fibrinogen scans. A total of 130 patients endured the trial and the results were registered on a sequential diagram. This showed that the 0-hypothesis could not be rejected, and that consequently no difference in the frequency of deep-vein thrombosis was detected.

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