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Clinical Trial
. 1980 Mar;73(3):197-9.
doi: 10.1177/014107688007300308.

Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication

J Bancewicz, K C Calman, S G Macpherson, C S McArdle, J G McVie, M Soukop
Clinical Trial

Adjuvant chemotherapy and immunotherapy for colorectal cancer: preliminary communication

J Bancewicz et al. J R Soc Med. 1980 Mar.

Abstract

Following surgical resection of Dukes' B or C colorectal cancers 72 patients have been randomly allocated to receive: 5-fluorouracil; or 5-fluorouracil and levamisole; or no treatment. Adjuvant treatment was continued for one year. 66 patients remain evaluable for up to 24 months. Preliminary results show no significant differences in survival or recurrence rates. Two patients receiving 5-fluorouracil and levamisole developed severe, but reversible, neutropenia. Other side effects were uncommon.

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