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. 1981 Apr;362(4):453-7.

A novel alkaline proteinase associated with the actomyosin complex from pig uterine myometrium

  • PMID: 7016711

A novel alkaline proteinase associated with the actomyosin complex from pig uterine myometrium

E G Afting et al. Hoppe Seylers Z Physiol Chem. 1981 Apr.

Abstract

A novel proteolytic activity has been demonstrated an partially characterized in the actomyosin complex isolated from smooth uterine muscle. This proteolytic activity showed an alkaline pH optimum, was inhibited by SH-group-blocking reagents but not by metal-chelating agents and copurified with the actomyosin complex. An important characteristic of this alkaline proteolytic activity was that it seems to hydrolyze the actomyosin by limited proteolysis with a concomitant loss of the myosin adenosinetriphosphatase activity.

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