In vitro methods for detection of circulating immune complexes
- PMID: 7018370
In vitro methods for detection of circulating immune complexes
Abstract
The possible pathologic consequences of the presence of circulating immune complexes in certain disease states has caused considerable attention to be given to the development of laboratory procedures capable of quantitatively measuring the presence of immune complexes in serum. Many assays are available which utilize differing properties of immune complexes for their detection. Examples of assays which depend on different biologic properties of circulating immune complexes are presented and discussed. Included are the Raji cell assay, Clq binding assay, inhibition of rheumatoid agglutination, and nephelometric assays for determination of circulating immune complexes.
Similar articles
-
Detection of immune complexes. The use of radioimmunoassays with Clq and monoclonal rheumatoid factor.J Clin Invest. 1977 May;59(5):990-1001. doi: 10.1172/JCI108722. J Clin Invest. 1977. PMID: 323292 Free PMC article.
-
[Detection of circulating immune complexes by immunoenzyme assay with solid phase Clq].Rev Med Chil. 1984 Jun;112(6):547-52. Rev Med Chil. 1984. PMID: 6393265 Spanish. No abstract available.
-
[Rheumatoid factors, C-reactive protein and circulating immunocomplexes: laser-nephelometric determination using the latex aggregation method. Preliminary evaluation in rheumatoid arthritis].Minerva Med. 1987 Dec 15;78(23):1775-8. Minerva Med. 1987. PMID: 3696453 Italian.
-
[Significance of the immune complex reaction in internal medicine].Z Gesamte Inn Med. 1980 Jan 15;35(2):49-57. Z Gesamte Inn Med. 1980. PMID: 6447414 Review. German.
-
Immunologic techniques utilized in the diagnosis of occupational lung disease.Clin Chest Med. 1983 Jan;4(1):85-95. Clin Chest Med. 1983. PMID: 6404586 Review.