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Review
. 1981 Jul 30;292(5822):413-17.
doi: 10.1038/292413a0.

Actions of cholera toxin and the prevention and treatment of cholera

J Holmgren
Review

Actions of cholera toxin and the prevention and treatment of cholera

J Holmgren. Nature. .

Abstract

The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the result of reasonably well understood cellular and biochemical actions of the toxin secreted by Vibrio cholerae. Based on this understanding it is possible to devise new techniques for the treatment and prophylaxis of cholera to complement those based on fluid replacement therapy and sanitation.

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