Applications of 13C NMR to metabolic studies

Abstract

It is our view that the above examples, most of which have been published in the last two years, represent the beginnings of a new field and that in spite of major problems in instrumentation and programming, the essential feasibility of using enriched 13C substrates for metabolic processes as a noninvasive technique has been firmly established. With the caveat that a rigorous protocol for signal assignment must be devised, we can look forward to many applications of this method in a wide range of biological systems.