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Comparative Study
. 1978 Oct;67(10):1355-7.
doi: 10.1002/jps.2600671005.

Comparison of effects of quinidine and dihydroquinidine on canine heart

T Balazs, E Herman, J Atkinson
Comparative Study

Comparison of effects of quinidine and dihydroquinidine on canine heart

T Balazs et al. J Pharm Sci. 1978 Oct.

Abstract

Various cardiac effects of quinidine and dihydroquinidine were tested in isolated dog hearts and in vivo in dogs. No significant differences were found in the negative inotropic, chronotropic, and dromotropic effects. Dihydroquinidine was more potent than quinidine in decreasing coronary arterial pressure.

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