[Synthesis and localization of alpha fetoprotein in liver regeneration in mice]
[Article in
Russian]
- PMID: 70239
Item in Clipboard
[Synthesis and localization of alpha fetoprotein in liver regeneration in mice]
[Article in
Russian]
Biull Eksp Biol Med.
1976 Oct.
Abstract
Typical mature hepatocytes constituting not over several per cent of the total amount of preserved hepatocytes served as the principal site of the alpha-fetoprotein (AFP) localization in the liver of mice regenerating after the CCl4 poisoning or partial hepatectomy. Morphologically they failed to differ from the principal mass of hepatocytes and retained an antigen of the bile capillaries on the surface. A change id to the dynamics of the AFP level in the animal serum. Apparently in regeneration of the mouse liver the principal AFP production was realized by mature hepatocytes.
Similar articles
-
[Atypical alpha fetoprotein-synthesizing cells in the regenerating mouse liver].Biull Eksp Biol Med. 1982 Jul;94(7):82-4. Biull Eksp Biol Med. 1982. PMID: 6181827 Russian.
-
[Liver structure as a possible factor in the regulation of alpha-fetoprotein synthesis].Biull Eksp Biol Med. 1979 Jun;87(6):576-9. Biull Eksp Biol Med. 1979. PMID: 88968 Russian.
-
Differential mechanisms of increased alpha 1-fetoprotein production in rats following carbon tetrachloride injury and partial hepatectomy.Cancer Res. 1976 Jul;36(7 PT 1):2171-5. Cancer Res. 1976. PMID: 58715
-
Alpha-fetoprotein production by the synchronized regenerating murine liver. Its independence on the phases of the mitotic cycle.Oncodev Biol Med. 1981;2(1-2):89-99. Oncodev Biol Med. 1981. PMID: 6170954
-
Cellular aspects of alpha-fetoprotein reexpression in tumors.Semin Cancer Biol. 1999 Apr;9(2):95-107. doi: 10.1006/scbi.1998.0084. Semin Cancer Biol. 1999. PMID: 10202131 Review.