Comparative Study
[Histamine-liberating action of MCD-peptide from bee venom]
[Article in
Russian]
- PMID: 70248
Item in Clipboard
Comparative Study
[Histamine-liberating action of MCD-peptide from bee venom]
[Article in
Russian]
Biull Eksp Biol Med.
1977 Jul.
Abstract
Histamine release (HR) from the isolated rat mast cells induced by MCD-peptide, mellitin (from the Apis mellifica venom) and compound 48/80 was studied. The dose-response curve, the latent period and temperature dependence of HR induced by MCD-peptide were similar to those of HR induced by compound 48/80. The HR induced by MCD-peptide proved to be an energy-dependent process that was independent of cyclic adenosine-3',5'-monophosphate.
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