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Comparative Study
. 1977 Jul;84(7):78-80.

[Histamine-liberating action of MCD-peptide from bee venom]

[Article in Russian]
I S Gushchin, A I Miroshnikov, V I Martynov
  • PMID: 70248
Comparative Study

[Histamine-liberating action of MCD-peptide from bee venom]

[Article in Russian]
I S Gushchin et al. Biull Eksp Biol Med. 1977 Jul.

Abstract

Histamine release (HR) from the isolated rat mast cells induced by MCD-peptide, mellitin (from the Apis mellifica venom) and compound 48/80 was studied. The dose-response curve, the latent period and temperature dependence of HR induced by MCD-peptide were similar to those of HR induced by compound 48/80. The HR induced by MCD-peptide proved to be an energy-dependent process that was independent of cyclic adenosine-3',5'-monophosphate.

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