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. 1981 Jul 10;9(13):3077-88.
doi: 10.1093/nar/9.13.3077.

Yeast ochre suppressor SUQ5-ol is an altered tRNA Ser UCA

C Waldron, B S Cox, N Wills, R F Gesteland, P W Piper, D Colby, C Guthrie

Yeast ochre suppressor SUQ5-ol is an altered tRNA Ser UCA

C Waldron et al. Nucleic Acids Res. .

Abstract

Ochre suppressor tRNA was partially purified from strains of Saccharomyces cerevisiae containing the serine-inserting class III suppressor SUQ5-ol. RNA sequence analysis of this tRNA indicated that the suppressor is derived from a UCA-decoding tRNA Ser by a G leads to U substitution in the middle position of the anticodon. The suppressor further differs from the wild-type UCA-decoding tRNA Ser in that the mutant anticodon lacks the modified uridine found in the wobble position of the wild-type tRNA and contains instead another modification in or near the anticodon.

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