Flow microcalorimetric bioassay of polyene antibiotics: interaction with growing Saccharomyces cerevisiae
- PMID: 7026271
- DOI: 10.1007/BF01985663
Flow microcalorimetric bioassay of polyene antibiotics: interaction with growing Saccharomyces cerevisiae
Abstract
Microcalorimetric investigation of the interaction of polyene antibiotics with mid-exponential cells of a growing culture of Saccharomyces cerevisiae has been used as the basis of a bioassay procedure. The assay is rapid, sensitive and reproducible. The results are compared to classical assays and potency ranking orders.