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Comparative Study
. 1981 Nov;68(5):1331-7.
doi: 10.1172/jci110380.

Reactivity of a monoclonal antibody with human ovarian carcinoma

R C Bast Jr, M Feeney, H Lazarus, L M Nadler, R B Colvin, R C Knapp
Comparative Study

Reactivity of a monoclonal antibody with human ovarian carcinoma

R C Bast Jr et al. J Clin Invest. 1981 Nov.

Abstract

A murine monoclonal antibody (OC125) has been developed that reacts with each of six epithelial ovarian carcinoma cell lines and with cryopreserved tumor tissue from 12 of 20 ovarian cancer patients. By contrast, the antibody does not bind to a variety of nonmalignant tissues, including adult and fetal ovary. OC125 reacts with only 1 of 14 cell lines derived from nonovarian neoplasms and has failed to react with cryostat sections from 12 nonovarian carcinomas.

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References

    1. Am J Obstet Gynecol. 1977 Apr 1;127(7):705-10 - PubMed
    1. Cancer. 1977 Feb;39(2):514-26 - PubMed
    1. Cancer. 1978 Jun;41(6):2335-40 - PubMed
    1. Int J Cancer. 1978 May 15;21(5):570-7 - PubMed
    1. J Clin Invest. 1978 Aug;62(2):302-10 - PubMed

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