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. 1981;182(3):511-3.
doi: 10.1007/BF00293945.

Are pyrimidine dimers non-instructive lesions?

C W Lawrence

Are pyrimidine dimers non-instructive lesions?

C W Lawrence. Mol Gen Genet. 1981.

Abstract

Published data from yeast and E. coli show that base substitution induced by UV in pyrimidine-pyrimidine sequences is not random, and suggest that fidelity of DNA replication is not entirely lost during transdimer synthesis. These observations question whether cyclobutane pyrimidine dimers are truly non-instructive lesions.

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