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Comparative Study
. 1980 Dec;12(6):776-9.
doi: 10.1128/jcm.12.6.776-779.1980.

Rapid detection of Clostridium difficile toxin in human feces

R W Ryan, I Kwasnik, R C Tilton
Comparative Study

Rapid detection of Clostridium difficile toxin in human feces

R W Ryan et al. J Clin Microbiol. 1980 Dec.

Abstract

Fifty fecal specimens were tested by three methods, bacterial isolation, counterimmunoelectrophoresis, and tissue culture, for Clostridium difficile and its toxin. Ten specimens (20%) were positive by all three methods. An additional eight specimens were toxin positive only by counterimmunoelectrophoresis. Although counterimmunoelectrophoresis and tissue culture are of equivalent sensitivity, the additional dilution necessary for tissue culture assay may be critical when only small concentrations of toxin are present.

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References

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    1. N Engl J Med. 1978 Mar 9;298(10):531-4 - PubMed
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