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. 1981 Sep-Dec;13(3-4):191-201.
doi: 10.1016/0010-468x(81)90098-2.

A program package for quantitative analysis of histologic structure and remodeling dynamics of bone

A program package for quantitative analysis of histologic structure and remodeling dynamics of bone

R C Manaka et al. Comput Programs Biomed. 1981 Sep-Dec.

Abstract

Quantitative bone histology has become an increasingly valuable tool for the management and diagnosis of metabolic bone disease. A new computer-assisted method for quantitative analysis of bone histology which combines the advantages of discriminatory input by the investigator with a significant reduction of evaluation time is presented. These programs allow the analysis of a sufficient number of subjects from different populations for the establishment of normative data, and are useful in the diagnosis and documentation of the treatment of metabolic bone disease.

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