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. 1981 Sep 1;197(3):747-9.
doi: 10.1042/bj1970747.

The effect of inorganic phosphate on the stability of some enzymes

M Rippa, M Signorini, T Bellini

The effect of inorganic phosphate on the stability of some enzymes

M Rippa et al. Biochem J. .

Abstract

In the presence of 5nM-P1, 6-phosphogluconate dehydrogenase from the yeast Candida utilis is more resistant to proteolysis and to the inactivating action of some chemical and physical agents. P1 also protects other enzymes against proteolysis. A hypothesis for the mechanism of the stabilizing action of P1 is advanced.

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