[Indirect immunofluorescence reaction study of systemic and local humoral immunity in patients with chronic inflammatory lung disease. I. Serological study results with Streptococcus pneumoniae autostrains]

Abstract

In the serological study of chronic bronchitis at the stage of exacerbation, carried out by means of the indirect immunofluorescence test with the use of Str. pneumoniae autostrains, 90.3 +/- 4% of the patients showed correlation between the presence of pneumococci in the bronchial contents and the systemic immunological reaction to this infective agent. At the acute stage of chronic bronchitis high antibody titers (1 : 1280 - 1 : 5120) prevailed, and the repeated study revealed the 4-fold and greater growth of the initial antibody titers in 35.7 +/- 6.4% of the patients. Antipneumococcal immunity in chronic bronchitis was found to have a pronounced type-specific character.