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Clinical Trial
. 1982 Mar;33(2):161-3.
doi: 10.1016/s0009-9260(82)80049-4.

A controlled clinical trial in advanced ovarian cancer

M Adams, K A Johansen, K W James, I Rocker
Clinical Trial

A controlled clinical trial in advanced ovarian cancer

M Adams et al. Clin Radiol. 1982 Mar.

Abstract

Thirty-eight patients with an advanced ovarian cancer (FIGO stage III and IV) were randomly allocated to treatment, either with melphalan (M) or a combination of adriamycin, 5-fluorouracil and cyclophosphamide (CAF) to determine the effect on survival. Actuarial survival of the two treatment groups was the same but the combination was more toxic.

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