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. 1977 Jun;16(3):725-9.
doi: 10.1128/iai.16.3.725-729.1977.

Adjuvanticity (immunity-inducing property) of cord factor in mice and rats

R Saito, S Nagao, M Takamoto, K Sugiyama, A Tanaka

Adjuvanticity (immunity-inducing property) of cord factor in mice and rats

R Saito et al. Infect Immun. 1977 Jun.

Abstract

Cord factor, a glycolipid in mycobacteria, was found to make a tolerogenic protein antigen immunogenic when injected 0 to 2 days before tolerogen injection in mice and rats. Cord factor was also found to increase phagocytic function of the reticuloendothelial system of mice, and the relationship between the immunity-inducing capacity and the phagocytic function is discussed.

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