Adjuvanticity (immunity-inducing property) of cord factor in mice and rats
- PMID: 70404
- PMCID: PMC421020
- DOI: 10.1128/iai.16.3.725-729.1977
Adjuvanticity (immunity-inducing property) of cord factor in mice and rats
Abstract
Cord factor, a glycolipid in mycobacteria, was found to make a tolerogenic protein antigen immunogenic when injected 0 to 2 days before tolerogen injection in mice and rats. Cord factor was also found to increase phagocytic function of the reticuloendothelial system of mice, and the relationship between the immunity-inducing capacity and the phagocytic function is discussed.
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