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Clinical Trial
. 1981 Dec;12(6):883-6.
doi: 10.1111/j.1365-2125.1981.tb01325.x.

Indapamide and bendrofluazide: a comparison in the management of essential hypertension

R F Bing, G I Russell, J D Swales, H Thurston
Clinical Trial

Indapamide and bendrofluazide: a comparison in the management of essential hypertension

R F Bing et al. Br J Clin Pharmacol. 1981 Dec.

Abstract

1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension. 2 Indapamide (2.5 mg a day) and bendrofluazide (5 mg a day) produced a significant but equivalent fall in blood pressure. 3 Both drugs caused a reduction in body weight and serum potassium with a rise in plasma renin activity but there were no other major side effects. 4 In twelve patients treated with a combination of indapamide and bendrofluazide there was no additional fall in mean blood pressure or serum potassium compared to treatment with bendrofluazide or indapamide alone.

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