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. 1982 Apr;63(2):207-13.

Expression of Ia antigen on epidermal keratinocytes is a consequence of cellular immunity

A J Suitters, I A Lampert

Expression of Ia antigen on epidermal keratinocytes is a consequence of cellular immunity

A J Suitters et al. Br J Exp Pathol. 1982 Apr.

Abstract

Ia antigen is seen in the normal epidermis only in Langerhans cells. However, when there is damage to the epidermis induced by cellular immunity Ia is expressed in the keratinocytes. This phenomenon is not seen in trauma or chemical inflammation. It is suggested that the expression of Ia in keratinocytes is due to cellular immunity possibly due to a lymphokine.

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References

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