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. 1982 Apr;2(4):223-7.
doi: 10.1007/BF01136720.

Immunofluorescence localization of type-M collagen in articular cartilage

V C Duance, M Shimokomaki, A J Bailey

Immunofluorescence localization of type-M collagen in articular cartilage

V C Duance et al. Biosci Rep. 1982 Apr.

Abstract

Normal mammalian articular cartilage has been found to contain several collagenous peptide chains in addition to type-II collagen. We now report the distribution in adult pig cartilage of one of these new peptides, type-M collagen, using type-specific antibodies. Type M is primarily located in the pericellular environment of the cells in the deeper zones of the articular cartilage. The distribution is shown to be distinct from that of type-II collagen. This finding suggests that type-M collagen may play an important role in the metabolism of articular cartilage.

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