Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Sep;5(9):3141-56.
doi: 10.1093/nar/5.9.3141.

Nucleotide sequence of the O gene and of the origin of replication in bacteriophage lambda DNA

G Scherer
Free PMC article

Nucleotide sequence of the O gene and of the origin of replication in bacteriophage lambda DNA

G Scherer. Nucleic Acids Res. 1978 Sep.
Free PMC article

Abstract

The nucleotide sequence of the O gene in bacteriophage lambda DNA is presented. According to two possible initiator codons, the primary structure of the O protein deduced from the DNA sequence consists of 278 or 299 amino acid residues. Structure and function of the O protein--one of the two phage initiator proteins for lambda DNA replication--are discussed in the light of a secondary structure model for the O protein. The central part of the O gene contains a cluster of symmetrical sequences extending over 160 base pairs. The point mutation of the cis-dominant replication mutant ti12 is located in this region.

PubMed Disclaimer

References

    1. Virology. 1964 Nov;24:241-53 - PubMed
    1. Nucleic Acids Res. 1978 May;5(5):1479-85 - PubMed
    1. Curr Top Microbiol Immunol. 1977;78:201-37 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Feb;74(2):689-93 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 Mar;75(3):1081-5 - PubMed

Associated data