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. 1982 Jan;21(1):125-30.
doi: 10.1128/AAC.21.1.125.

In vivo inhibition of respiratory syncytial virus by ribavirin

J F Hruska, P E Morrow, S C Suffin, R G Douglas Jr

In vivo inhibition of respiratory syncytial virus by ribavirin

J F Hruska et al. Antimicrob Agents Chemother. 1982 Jan.

Abstract

Ribavirin reduced the amount of respiratory syncytial virus in nasal turbinates and lung tissues of experimentally infected cotton rats by over 90%. An effect was seen when the drug was given either intraperitoneally or by aerosol; however, the antiviral effect was achieved at much lower doses when delivered by the aerosol route. No animal deaths due to the drug were seen.

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References

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