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. 1982 Apr 16;29(2):105-10.
doi: 10.1016/0304-3940(82)90337-8.

Localization of neuronal histamine in rat brain

B J Wilcox, V S Seybold

Localization of neuronal histamine in rat brain

B J Wilcox et al. Neurosci Lett. .

Abstract

Antisera to histamine were generated by immunization of albino guinea pigs with a complex of histamine and methylated-bovine serum albumin. Characterization of the antisera and preliminary mapping of histaminergic neurons were conducted on brain tissue from normal and experimentally manipulated rats. Using immunofluorescence, histamine-like immunoreactive cell bodies were revealed in the lateral hypothalamus, and fibers were stained in the hypothalamus, cortex, amygdala and hippocampus.

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