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. 1982 Sep;66(3):513-4.
doi: 10.1161/01.cir.66.3.513.

Preoperative and postoperative renin levels in coarctation of the aorta

Preoperative and postoperative renin levels in coarctation of the aorta

F B Parker Jr et al. Circulation. 1982 Sep.

Abstract

We studied plasma renin activity (PRA) in eight children before and after surgical correction of aortic coarctation. These eight children underwent a combination of low-sodium diet and diuresis before surgery, and PRA was measured shortly thereafter. Thirty-two to 51 months after successful surgical correction, PRA was measured again. The mean PRA was 21.4 +/- 1.3 ng/ml/hour (+/- SD) preoperatively and 5.5 +/- 1.5 ng/ml/hour postoperatively. These findings provide further evidence of the significance of increased renin-angiotensin activity in patients with aortic coarctation.

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