[Genetic control of recombination processes in Aspergillus nidulans. IV. The effect of uvs mutations on the frequency of spontaneous and nitrosomethylurea-induced intragenic mitotic recombination]

Abstract

Effects of three uvs mutations were studied on spontaneous and nitrosomethyl-induced intragenic mitotic segregation in the methA region of the chromosome II in Aspergillus diploids homozygous for uvs and heteroallelic for methA mutation. The reversion frequencies of methA alleles in parent haploid strains were also determined. All the mutations increased the frequency of spontaneous and decreased that of induced intragenic mitotic recombination. The frequency of spontaneous reversions was decreased in uvs haploids. The interaction between repair, recombination and mutagenesis processes in Aspergillus nidulans is discussed.