[Study of the three-dimensional structure of proteins by means of tritium labeling. II. Intramolecular distribution of tritium in the N-terminal part of myoglobin and the tertiary structure of protein]
- PMID: 7048065
[Study of the three-dimensional structure of proteins by means of tritium labeling. II. Intramolecular distribution of tritium in the N-terminal part of myoglobin and the tertiary structure of protein]
Abstract
The possible use of the method of 3H-label introduction by means of a 3H-atom beam for investigating the three-dimensional structure (surface) of proteins was studied. The intramolecular distribution of tritium in the N-terminal part of 3H-labelled sperm-whale myoglobin was studied. The results obtained are in good agreement with the X-ray analysis data on the polypeptide chain of the protein molecule. The possible use of this method for constructing precise three-dimensional models of polypeptides and proteins is discussed.