doi: 10.1016/0378-4274(82)90166-7.
Mutagenicity of three aromatic amines in the presence of fractions from various tissues
- PMID: 7048632
- DOI: 10.1016/0378-4274(82)90166-7
Item in Clipboard
Mutagenicity of three aromatic amines in the presence of fractions from various tissues
Toxicol Lett.
1982 May.
Abstract
The mutagenic activity of 2-aminofluorene, 4-aminobiphenyl and 3,2'-dimethylaminobiphenyl towards Salmonella typhimurium strain TA1538 was tested in the presence of post-mitochondrial fractions of liver, kidney, intestine, colon and testicle from untreated and pretreated rats. The metabolic activation capacity of these various fractions was very different. In the experimental conditions, no relationship was found between the mutagenic activity and the carcinogenicity of the three aromatic amines.
Similar articles
-
Liver, kidney and small-intestine microsomal-mediated mutagenicity of carcinogenic aromatic amines.Mutat Res. 1984 Jan;125(1):23-31. doi: 10.1016/0027-5107(84)90028-9. Mutat Res. 1984. PMID: 6361544
-
Activation of aromatic amines to mutagens by various animal species including man.Mutat Res. 1983 Dec;124(3-4):325-36. doi: 10.1016/0165-1218(83)90203-3. Mutat Res. 1983. PMID: 6361543
-
Activation of some aromatic amines to mutagenic products by human red blood cell cytosol.Mutat Res. 1991 Aug;263(4):249-55. doi: 10.1016/0165-7992(91)90009-s. Mutat Res. 1991. PMID: 1861690
-
Differences in the ferrihemoglobin-forming capabilities and carcinogenicities between monocyclic and polycyclic N-acylarylamines and their derivatives.Q Rev Drug Metab Drug Interact. 1982;4(2-3):171-236. doi: 10.1515/dmdi.1982.4.2-3.171. Q Rev Drug Metab Drug Interact. 1982. PMID: 6765364 Review. No abstract available.
-
Perspectives on the mechanism of action of the splenic toxicity of aniline and structurally-related compounds.Food Chem Toxicol. 1987 Aug;25(8):619-26. doi: 10.1016/0278-6915(87)90024-x. Food Chem Toxicol. 1987. PMID: 3305247 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
